trans-4-hydroxy-L-proline CHEBI 18095

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CharChem Amino acids

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trans

This MassBank Record with Accession OUF00473 contains the MS mass spectrum of 'trans-4-Hydroxy-L-proline' with the compound class 'Natural Product' The mass spectrum was acquired on a GC-EI-TOF with POSITIVE ionisation and has the SPLASH 'splash10-000x-0950000000-c46b5bba0f41001e3c18'

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T3DB: 4

Shibasaki T Mori H Ozaki A: Enzymatic production of trans-4-hydroxy-L-proline by regio- and stereospecific hydroxylation of L-proline Biosci Biotechnol Biochem 2000 Apr 64(4):746-50 Pickersgill IF Rapoport H: Preparation of functionalized conformationally constrained DTPA analogues from L- or D-serine and trans-4-hydroxy-L-proline

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Hydroxyproline

Hydroxyproline is a neutral heterocyclic protein amino acid It is found in collagen and as such it is common in many gelatin products Hydroxyproline is mostly used as a diagnostic marker of bone turnover and liver fibrosis Therapeutically hydroxyproline is being studied as an an experimental medicine but is approved in France as a combination topical gel product called Cicactive for small

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Hydroxyproline

Hydroxyproline is a neutral heterocyclic protein amino acid It is found in collagen and as such it is common in many gelatin products Hydroxyproline is mostly used as a diagnostic marker of bone turnover and liver fibrosis Therapeutically hydroxyproline is being studied as an an experimental medicine but is approved in France as a combination topical gel product called Cicactive for small

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CharChem Amino acids

Amino acids Find chemicals by name or formulas Categories This reference contains the names of substances and descriptions of the chemical formulas (including the structural formula and the skeletal formula) Type the part of name or the formula of substance for search:

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GitHub

has part BFO:0000051 chebi_ontology false has_part has_part electron-1 0 000548579903 CHEBI:10545 Elementary particle not affected by the strong force having a spin 1/2 a negative elementary charge and a rest mass of 0 000548579903(13) u or 0 51099906(15) MeV KEGG:C05359 PMID:21614077 [*-] beta beta(-) beta-particle chebi_ontology e e(-) e-electron negatron 2-hydroxyglutarate(2-)-2 146 022

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Helmholtz Zentrum Mnchen

trans-4-Hydroxy-L-proline C01157 HMDB00725 51-35-4 4hpro-LT #55 3-Ureidoisobutyrate CH4N2O 57-13-6 3uib #56 2-hydroxyisobutyrate HMDB00729 594-61-6 #57 2-methylbutyroylcarnitine C12H23NO4 HMDB00378 31023-25-3 #58 3-hydroxy-2-ethylpropionate C5H10O3 HMDB00396 4374-62-3 #59 3-Methyl-2-oxobutanoic acid C5H8O3 C00141 HMDB00019 3715-29-5 759-05-7

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has part BFO:0000051 chebi_ontology false has_part has_part electron-1 0 000548579903 CHEBI:10545 Elementary particle not affected by the strong force having a spin 1/2 a negative elementary charge and a rest mass of 0 000548579903(13) u or 0 51099906(15) MeV KEGG:C05359 PMID:21614077 [*-] beta beta(-) beta-particle chebi_ontology e e(-) e-electron negatron 2-hydroxyglutarate(2-)-2 146 022

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Hidroxiprolina

La hidroxiprolina es un aminocido no esencial constituyente de protenas y derivado de la prolina Para esta hidroxilacin existe una enzima llamada prolil-hidroxilasa que reconoce a la prolina como su sustrato La condicin es que la prolina (Pro) a hidroxilar se encuentre vecina a una glicina (Gly) en la hebra en el sentido amino a carboxilo

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GMD

ChEBI:18095: ChEBI ontology: has role metabolite: ChEBI ontology: is a 4-hydroxyproline: ChEBI ontology: is tautomer of trans-4-hydroxy-L-proline zwitterion: ChemSpider ID: 5605: MAPMAN: Hydroxyproline: MetaCyc: 4-HYDROXY-L-PROLINE: PubChem CID: 5810: PubChem SID: 92297722: synonym (2S 4R)-4-hydroxy-2-pyrrolidinecarboxylic acid: synonym (2S 4R

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Hydroxyproline

Hydroxyproline is a nonessential amino acid derivative formed during post-translational protein modification through hydroxylation of the amino acid proline by the enzyme prolyl hydroxylase which requires vitamin C as a co-factor Hydroxyproline is a major component of the protein collagen and plays a key role in the stability of the collagen triple helix

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T3DB: 4

Shibasaki T Mori H Ozaki A: Enzymatic production of trans-4-hydroxy-L-proline by regio- and stereospecific hydroxylation of L-proline Biosci Biotechnol Biochem 2000 Apr 64(4):746-50 Pickersgill IF Rapoport H: Preparation of functionalized conformationally constrained DTPA analogues from L- or D-serine and trans-4-hydroxy-L-proline

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trans

ChEBI Ontology Outgoing trans-4-hydroxy-L-proline (CHEBI:18095) has role human metabolite (CHEBI:77746) trans-4-hydroxy-L-proline (CHEBI:18095) has role mouse metabolite (CHEBI:75771) trans-4-hydroxy-L-proline (CHEBI:18095) has role plant metabolite (CHEBI:76924) trans-4-hydroxy-L-proline (CHEBI:18095) is a 4-hydroxyproline (CHEBI:20392) trans-4-hydroxy-L-proline (CHEBI:18095

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trans

trans-4-hydroxy-l-proline hydroxyproline l-hydroxyproline 2s 4r-4-hydroxypyrrolidine-2-carboxylic acid 4-hydroxy-l-proline l-4-hydroxyproline hydroxy-l-proline trans-4-hydroxyproline h-hyp-oh hypro: ChEBI: CHEBI:18095: SMILES: C1C(CNC1C(=O)O)O: Molecular Formula: C 5 H 9 NO 3: InChI Key: PMMYEEVYMWASQN-DMTCNVIQSA-N: PubChem CID: 5810

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Hydroxyproline ingestion and urinary oxalate and glycolate

RESULTS The mean circulating concentration of hydroxyproline in individuals when consuming self-selected diets was 13 25 7 μM (Table 1) A broad range of values was detected spanning 4 8−23 8 μM suggesting inter-individual differences in collagen turnover hydroxyproline metabolism and/or hydroxyproline intake With the ingestion of 30 g of gelatin containing 2 75 g hydroxyproline each

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