5

5-thio-D-glucose Regulatory process names 1 Other identifiers 1 EC / List no : 243-798-8 CAS no : 20408-97-3 Mol Formula: Help Key datasets Brief Profile REACH registered substance factsheets CL Inventory Biocidal active substance factsheets PACT tool Regulatory Obligations

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Development new radiopharmaceutical based on 5

The article considers the obtaining and possibility of using 5-thio-D-glucose labeled technetium-99m for the diagnosis of malignant tumors by single photon emission computed tomography The analysis of the level of international developments of radiopharmaceuticals based

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Cytotoxic effect of 5

Abstract The effect of 5-thio-D-glucose on chronically hypoxic cells in the multicell spheroids of Chinese hamster V79 cells was investigated The radiation survival curves of spheroid cells indicated that most of the chronically hypoxic cells in the spheroids could be eliminated by incubating the spheroids with 5-20 mM of 5-thio-D-glucose or 17 hours

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Effects of 5

Abstract Glucose provides more than 50% of human caloric requirements and is the principal carbohydrate metabolite of most organisms 5-Thio-D-glucose (Fig 3 1) is the nearest chemical analogue of natural D-glucose with only a sulphur atom replacing the oxygen atom in the pyranose ring structure This sulphur sugar is conformationally and chemically similar to D-glucose but is quite D

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KoreaMed

To evaluate the radioprotective effects of 5-thio-D-glucose(5-TDG) on normal skin an experimental study was carried out with total 140 mice of which 30 mice were given 5-TDG followed by irradiation and 60 mice were given intraperitoneally (IP) two hours before irradiation and the radiation doses were singly 2500 3500 or 4500 radsrespectively

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5

Adult male mice were administered several doses of 5-thio-D-glucose (5-TG) at two environmental temperatures 4 and 22 degrees C Both intracerebroventricular (icv) and intraperitoneal (ip) administration of 5-TG resulted in significant (P 0 05 to P 0 001) decrements in rectal temperature (Tre) that were dose dependent

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KoreaMed

To evaluate the radioprotective effects of 5-thio-D-glucose(5-TDG) on normal skin an experimental study was carried out with total 140 mice of which 30 mice were given 5-TDG followed by irradiation and 60 mice were given intraperitoneally (IP) two hours before irradiation and the radiation doses were singly 2500 3500 or 4500 radsrespectively

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Selective Potentiation of Hyperthermic Killing of Hypoxic

The modification of cell lethality at elevated temperatures by 5-thio-d-glucose the nearest analog of d-glucose was studied with the use of HeLa cells in the presence or absence of oxygen When the cells were exposed to temperatures ranging from 40 5–42 for 0 5 to 4 hr in the presence of 5-thio-d-glucose (5 mm) there was a selective potentiation of hyperthermic killing of hypoxic cells

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Thio

Pyrolysis of 3 6-anhydro-1 2--isopropylidene-5--(methylthio)thiocarbonyl-α--glucofuranose and of the β---isomer gives low yields of the corresponding 5-(methylthio)carbonylthio-compounds the main product is 2-(hydroxyacetyl)furan The reaction of potassium thiobenzoate with 3 6-anhydro-1 2--isopropylidene-5-

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Alteration of glucose transport and diauxic growth in 5

Abstract Spontaneous mutants of Azotobacter vinelandii defective for glucose utilization were selected as resistant to 5-thio-D-glucose Mutant strains AM2 AM38 and AM39 exhibited longer generation times than the wild type when grown on glucose

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SAFETY DATA SHEET 5

SAFETY DATA SHEET 5-Thio-D-glucose According to Regulation (EC) No 1907/2006 Annex II as amended Commission Regulation (EU) No 2015/830 of 28 May 2015 SECTION 1: Identification of the substance/mixture and of the company/undertaking 1 1 Product identifier Product name 5-Thio-D-glucose Product number MT04882 CAS number 20408-97-3 EC number

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Biodistribution and pharmacokinetics of S

5-thio-D-glucose (5-TDG) exerts profound effects on rapidly metabolizing tissues The authors have used liquid scintillation counting to study the tissue distribution and pharmacokinetics of S-35-labeled 5-TDG in hamster models of pancreatic tumors

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Development new radiopharmaceutical based on 5

The article considers the obtaining and possibility of using 5-thio-D-glucose labeled technetium-99m for the diagnosis of malignant tumors by single photon emission computed tomography The analysis of the level of international developments of radiopharmaceuticals based on derivatives of glucose has been carried out Also the article provides information on of using experimental batches of

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5

5-Thio-D-glucose (5TG) is an antimetabolic glucose analogue in which sulphur is substituted for the pyranose ring oxygen Intracardiac infusion of 5TG caused dose-dependent increases in feeding and blood glucose concentrations in rats Increased food intake was elicited by molar doses of 5TG which were one-third those necessary to elicit feeding by 2-deoxy-D-glucose (2DG) 5TG also caused

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An Experimental Study on the Effect of 5

An Experimental Study on the Effect of 5-Thio-D-Glucose on Radiation Injury after Hyperthermia To evaluate the influence of 5-thio-D-glucose on irradiation effect after hyperthermia an experimental study was carried out using a total of 72 mice A single dose of 3000 rads was delivered on skin of mouse tail after hyperthermia with or without intraperitoneal injection of 5-thio-D-glucose 2

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Development new radiopharmaceutical based on 5

The article considers the obtaining and possibility of using 5-thio-D-glucose labeled technetium-99m for the diagnosis of malignant tumors by single photon emission computed tomography The analysis of the level of international developments of radiopharmaceuticals based

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CAS 108391

Product Name:5-THIO-D-GLUCOSE 6-PHOSPHATE DIAMMONIUM SALT Synonyms:5-THIO-D-GLUCOSE 6-PHOSPHATE DIAMMONIUM SALT 5-thio-D-glucose 6-phosphate diammonium 5-Thio-D-glucose-6-phosphate diammonium salt 97% CAS:108391-99-7 MF:C6H19N2O8PS MW:310 26 EINECS: Delivery:immediately Package: 25g 100g 1kg 25kg or according to customer's request If

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Inhibition of cellular transport processes by 5

Uptake of 5-thio-d-glucose is phlorrhizin-sensitive Na+-dependent and energy-dependent d-Galactose and methyl α-d-glucopyranoside transport is competitively inhibited by 5-thio-d-glucose with Ki values of 4 8 and 9 7mm respectively 5-Thio-d-glucose thus shows

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Side Effects of 5

Side Effects of 5-Thio-D-Glucose By James W Kalat See all Hide authors and affiliations Science 20 Dec 1974: Vol 186 Issue 4169 pp 1074 DOI: 10 1126/science 186 4169 1074 Article Info Metrics eLetters PDF This is a PDF-only article The first page of the PDF of this article appears

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