Toxicological Profile for Trichloroethylene TCE

TRICHLOROETHYLENE

Trichloroethylene is a colorless highly volatile liquid at ambient temperature and pressure It has a sweet chloroform-like odor Following exposure to trichloroethylene humans primarily experience central nervous system effects and irritation At high concentrations cardiac arrhythmias have also occurred The AEGL-1 derivation is based on the exposure of volunteers to 300 ppm for 2

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Revisiting Trichloroethylene Contaminated Hazardous

In January 2013 ATSDR finalized its Toxicological Profile addendum for trichloroethylene (TCE) which adopted the U S Environmental Protection Agency's (U S EPA) reference dose of 0 0005 mg/kg/day as its chronic oral minimal risk level (MRL) and the reference concentration of 2 [micro]g/[m sup 3] as its chronic inhalation MRL

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Trichloroethylene

The mutagenicity of trichloroethylene (TCE) has been extensively investigated in a number of in vitro and in vivo test systems The most comprehensive reviews of the mutagenicity of TCE have been published by Moore and Harrington-Brock (2000) in the EU Risk Assessment Report (2004) and in the EPA-IRIS Document on TCE (2009)

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HEALTH ALERT

Trichloroethylene (TCE) and Reproductive Risk February 2015 Summary TCE presents a risk to pregnant women and women of reproductive age at air concentrations well below OSHA's Permissible Exposure Level (PEL) Recent evidence suggests that TCE exposure during pregnancy can increase a baby's risk of cardiac

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VA agreed that trichloroethylene (TCE) likely as not

From the EPA Toxicological Review Of Trichloroethylene September 2001 Section 4 11 2 1 6 Although the summary evaluation focused on the scientific evidence and meta-analysis for kidney lymphoma and liver cancers there is also some suggestive evidence for TCE as a risk factor for cancer at other sites including bladder esophagus prostate cervix breast and childhood leukemia

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DEPARTMENT OF HEALTH HUMAN SERVICES Public Health

TCE--Q a c o 1 u o o UJ *~ 10000 1000 - 100 10 - 1 - 0 1-0 01 - 0 001 0 0001 - o 100 4- Approximate range of lowest level at which effects were observed in chronic animal studies (including cancer effect levels) 0 001 Source: lexicological Profile for Trichloroethylene (Update) U S Department of Health and Human Services

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ATSDR

26 09 2019The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects information for the hazardous substance described here Each peer-reviewed profile identifies and reviews the key literature that describes a hazardous substance's toxicologic properties Other pertinent literature is also presented but is described in less detail than the key studies

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Trichloroethylene and drinking water

trichloroethylene above 5 ppb should not be used for irrigating or watering 2 What about bathing and showering? Trichloroethylene can enter the body through the skin 2 Since trichloroethylene easily releases from water into the air bathing and showering with trichloroethylene-contaminated water may

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Toxicological Profile for Trichloroethylene

An update Toxicological Profile for Trichloroethylene was released in April 1993 This edition supersedes any previously released draft or final profile Toxicological profiles are revised and republished as necessary but no less than once every three years For information regarding the update status of previously released profiles contact

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Substance name:

TCE appears to be carcinogenic to multiple targets in rats mice and humans acting by a multiplicity of mechanisms mediated through a multiplicity of active metabolites Lacking clear understanding of the complexity of TCE carcinogenicity risk assessors again must rely on standard methods for lack of a better-supported methodology

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Health Profile on Trichloroethylene

Health Profile on Trichloroethylene 2 Executive Summary The chlorinated solvent trichloroethylene (also known as TRI TCE trichloroethene acetylene tri-chloride ethylene trichloride cancer in humans based on extensive toxicological and epidemiological research 2

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Trichloroethylene

Toxicological Profile for Trichloroethylene (Update) U S Public Health Service U S Department of Health and Human Services Atlanta GA 1997 2 U S Department of Health and Human Services Registry of Toxic Effects of Chemical Substances (RTECS online database)

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Revisiting trichloroethylene contaminated hazardous

In January 2013 ATSDR finalized its Toxicological Profile addendum for trichloroethylene (TCE) which adopted the U S Environmental Protection Agency's (U S EPA) reference dose of 0 0005 mg/kg/day as its chronic oral minimal risk level (MRL) and the reference concentration of 2 [micro]g/[m sup 3] as its chronic inhalation MRL

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Toxicological Summary for: Trichloroethylene (TCE)

Trichloroethylene - 1 Web Publication Date: October 2018 Toxicological Summary for: Trichloroethylene (TCE) CAS: 79-01-6 Synonyms: TCE Trichloroethene 1 1 2-Trichloroethene 1 1-Dichloro-2-Chloroethylene 1-Chloro-2 2-Dichloroethylene Acute Non-Cancer Health Based Value (nHBV Acute) = Not derived Acute exposures have produced

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ARCHIVED

Trichloroethylene (1 1 2-trichloroethene TCE CAS Registry No 79-01-6) is an unsaturated chlorinated aliphatic compound (chemical formula C 2 HCl 3) with a low molecular weight (131 4 g/mol) At room temperature it is a volatile nonviscous liquid (boiling point = 86 7C) with a higher density (1 46 g/mL [20C/4C]) and a lower surface tension (0 029 N/m) than water

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Methane and Trichloroethylene Degradation

Whole-cell assays of methane and trichloroethylene (TCE) consumption have been performed on Methylosinus trichosporium OB3b expressing particulate methane monooxygenase (pMMO) From these assays it is apparent that varying the growth concentration of copper causes a change in the kinetics of methane and TCE degradation For M trichosporium OB3b increasing the copper growth

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Tetrachloroethylene

Tetrachloroethylene also known under the systematic name tetrachloroethene or perchloroethylene and many other names (and abbreviations such as perc or PERC and PCE) is a chlorocarbon with the formula Cl 2 C=CCl 2 It is a colorless liquid widely used for dry cleaning of fabrics hence it is sometimes called dry-cleaning fluid It has a sweet odor detectable by most people at a

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ATSDR

ATSDR - Toxprofile: Toxicological Profile Information Sheet - Hallo friend FREE FROM DISEASE In the article you read this time with the title ATSDR - Toxprofile: Toxicological Profile Information Sheet we have prepared well for this article you read and download the information therein hopefully fill posts Artikel DIABETES Artikel GENERAL Artikel HEART Artikel LUNGS LUNGS Artikel

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Trichloroethylene Hr Direct

Draft Toxicological Profile for Trichloroethylene - Agency for Toxic Trichloroethylene (TCE) subregistry baseline through follow-up 3 technical report Agency for Toxic trichloroethylene and/or tetrachloroethylene in lettuce by direct headspace analysis ] Z Lebensm Unters +*Clearfield HR 1970 tp19-c9 pdf

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Supporting Documents for Trichloroethylene

Appendix D: Neurological Effects of Trichloroethylene (PDF) (115 pp 906 K) Appendix E: Analysis of Liver and Coexposure Issues for the TCE Toxicological Review (PDF) (397 pp 2 1 ) Appendix F: TCE Noncancer Dose-Response Analysis (PDF) (36 pp 519 K) Appendix G: TCE Cancer Dose-Response Analysis with Rodent cancer Bioassay Data (PDF) (37 pp

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TCE

toxicological profile for vinyl chloride: its occurrence products Using published policies and procedures ATSDR has established four chemical-specific subregistries - trichloroethane (TCA) trichloroethylene (TCE) benzene and dioxin - and is following approximately 10 000 registrants longitudinally (1-6)

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FACT SHEET Trichloroethylene (TCE)

Trichloroethylene (TCE) What is TCE? Trichloroethylene (try-klor'oh-eth'uh-leen) or TCE is a man-made chemical TCE is a colorless liquid with a sweet smell (ATSDR) 2014 Draft toxicological profile for trichloroethylene Atlanta GA: U S Department of

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